| Pair Name | Luteolin, Imatinib | ||
| Phytochemical Name | Luteolin (PubChem CID: 5280445 ) | ||
| Anticancer drug Name | Imatinib (PubChem CID: 123596 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Luteolin, Imatinib | |||
| Disease Info | [ICD-11: 2A20.1] | Chronic myelogenous leukemia | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| In Vitro Model | K-562 | Blast phase chronic myelogenous leukemia | Homo sapiens (Human) | CVCL_0004 |
| Result | The combination of some flavonoids and imatinib mesylate may increase the cytotoxic effect; However, the antagonistic effect should be considered in combined use on k562 cells. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method. Balkan Med J. 2019 Feb 28;36(2):96-105. doi: 10.4274/balkanmedj.galenos.2018.2017.1244. | Click |
